Your QuestionI have been recently diagnosed with antisynthetase syndrome, acute interstitial lung disease, muscle weakness, skin involvement, scleroderma, and dermatomyositis. Could you please provide me with information on antisynthetase syndrome? I am also interested in learning about prognosis, treatment, and clinical trials.
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Questions on this page
- What is antisynthetase syndrome?
- What symptoms are associated with antisynthetase syndrome?
- What causes antisynthetase syndrome?
- What prognosis is associated with antisynthetase syndrome?
- What treatment is available for antisynthetase syndrome?
- Are there any clinical trials for antisynthetase syndrome?
Symptoms of antisynthetase syndrome vary from person to person and may include :
You can search ClinicalTrials.gov for other trials by visiting their Web site and entering a disease or condition in their search box. Additionally, you can also contact the Patient Recruitment and Public Liaison (PRPL) Office at the National Institutes of Health (NIH). We recommend calling the toll-free number listed below to speak with a specialist, who can help you determine if there are any clinical trials for which an individual with antisynthetase syndrome may be eligible. If you are located outside the United States, and would like to be contacted via telephone, you will need to provide your telephone number in full, including area code and international dialing prefix.
Patient Recruitment and Public Liaison Office
NIH Clinical Center
Bethesda, Maryland 20892-2655
Web site: http://clinicalcenter.nih.gov/
To find helpful general information on clinical trials at the following ClinicalTrials.gov Web page.
A tutorial about clinical trials can be found at the following link from the National Library of Medicine:
Resources on many charitable or special-fare flights to research and treatment sites and low-cost hospitality accommodations for outpatients and family members, as well as ambulance services, are listed on the Web site of the Office of Rare Diseases (ORD), part of the National Institutes of Health.
- Tzioufas AG. Orphanet. November 2001; http://www.orpha.net/data/patho/Pro/en/Antisynthetase-FRenPro8611.pdf. Accessed 5/12/2008.
- Antisynthetase syndrome. Orphanet. May, 2014; http://www.orpha.net/consor/cgi-bin/Disease_Search.php?lng=EN&data_id=8611. Accessed 4/28/2015.
- Solomon J, Swigris JJ &, Brown KK. Myositis-related interstitial lung disease and antisynthetase syndrome. J Bras Pneumol. February, 2011; 37(1):100–109. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676869/. Accessed 4/28/2015.
- Harris: Kelley's Textbook of Rheumatology, 7th ed.. Philadelphia: Saunders, An Imprint of Elsevier; 2005;
- Di Martino SJ, Kagen LJ. Newer Therapeutic Approaches: Inflammatory Muscle Disorders. Rheumatic Diseases Clinics of North America. February 2006;