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Diseases

Genetic and Rare Diseases Information Center (GARD)

Antisynthetase syndrome


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Treatment

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What treatment is available for antisynthetase syndrome?

Corticosteroids are typically the first-line of treatment and may be required for several months or years. These medications are often given orally; however, in severe cases, intravenous methylprednisolone may be prescribe initially. Immunosuppressive medications may also be recommended, especially in people with severe muscle weakness or symptomatic interstitial lung disease. Physical therapy is often necessary to improve weakness, reduce further muscle wasting from disuse, and prevent muscle contractures.[1][2]
Last updated: 8/10/2015

References
  1. Antisynthetase syndrome. DermNet NZ. December 2014; http://dermnetnz.org/immune/antisynthetase.html.
  2. Chatterjee S, Prayson R, Farver C.. Antisynthetase syndrome: not just an inflammatory myopathy. Cleve Clin J Med. October 2013; 80(10):655-666.


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Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Antisynthetase syndrome. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.