Pemphigus is a group of rare autoimmune diseases that cause blistering of the skin and mucous membranes (mouth, nose, throat, eyes, and genitals). This condition can occur at any age, but often strikes people in middle or older age. It is more common in people of Middle Eastern or Jewish descent than in other races and cultures. Pemphigus is a chronic disease which is best controlled by early diagnosis and treatment. Treatment includes steroids to reduce inflammation, drugs that suppress the immune system response and antibiotics to treat associated infections.
There are three main types of pemphigus:
- Pemphigus. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). June 2015; http://www.niams.nih.gov/Health_Info/Pemphigus/default.asp. Accessed 9/1/2015.
- Pemphigus. MayoClinic.com. November 7, 2012; http://www.mayoclinic.org/diseases-conditions/pemphigus/basics/definition/con-20025041?DSECTION=all&p=1. Accessed 9/1/2015.
- Pemphigus. MedlinePlus. December 4, 2013; https://www.nlm.nih.gov/medlineplus/pemphigus.html. Accessed 9/1/2015.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
- MayoClinic.com provides information about pemphigus. Click on the above link to access this information.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Pemphigus. Click on the link to view a sample search on this topic.