Other Names for this Disease
- Chronic atrophic polychondritis
- Recurrent polychondritis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.
Cartilage is a tough but flexible tissue that covers the ends of bones at a joint, and gives shape and support to other parts of the body. Ear involvement is the most common feature, but a variety of other areas of the body may be affected, including the costal (rib) cartilage, eyes, nose, airways, heart, vascular (veins) system, skin, joints, kidney, and nervous system. The signs and symptoms vary from person to person depending on which parts of the body are affected. The exact underlying cause of RP is unknown; however, scientists suspect that it is an autoimmune condition. The primary goals of treatment for people with RP are to relieve present symptoms and to preserve the structure of the affected cartilage.Relapsing polychondritis (RP) is a rare condition characterized by recurrent inflammation of cartilage and other tissues throughout the body.
Last updated: 4/21/2015
- Puéchal X, Terrier B, Mouthon L, Costedoat-Chalumeau N, Guillevin L, Le Jeunne C. Relapsing polychondritis. Joint Bone Spine. March 2014; 81(2):118-124.
- Clement J Michet, MD. Clinical manifestations of relapsing polychondritis. UpToDate. February 2015; Accessed 4/21/2015.
- Relapsing Polychondritis. NORD. March 2012; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/561/viewAbstract.
- Clement J Michet, MD. Etiology and pathogenesis of relapsing polychondritis. UpToDate. October 2013;
- Relapsing polychondritis. DermNet NZ. December 2013; http://www.dermnetnz.org/dermal-infiltrative/relapsing-polychondritis.html.
- Nicholas Compton, MD. Polychondritis. Medscape Reference. March 2015; http://emedicine.medscape.com/article/331475-overview.
- DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
- The Merck Manual provides information on this condition for patients and caregivers.
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Merck Manual for health care professionals provides information on Relapsing polychondritis.
- MeSH® (Medical Subject Headings) is a terminology tool used by the National Library of Medicine. Click on the link to view information on this topic.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Relapsing polychondritis. Click on the link to view a sample search on this topic.