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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Relapsing polychondritis


Other Names for this Disease
  • Chronic atrophic polychondritis
  • Recurrent polychondritis
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Treatment

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How might relapsing polychondritis be treated?

The primary goals of treatment for people with relapsing polychondritis (RP) are to relieve present symptoms and to preserve the structure of the affected cartilage. The main treatment for RP is corticosteroid therapy with prednisone to decrease the severity, frequency and duration of relapses. Higher doses are generally given during flares, while lower doses can typically be prescribed during periods of remission. Other medications reported to control symptoms include dapsone, colchicine, azathioprine, methotrexate, cyclophosphamide, hydroxychloroquine, cyclosporine and infliximab.[1][2]

People who develop severe heart or respiratory complications may require surgery.[3]

More detailed information about the management of RP is available on Medscape Reference's Web site and can be viewed by clicking here.
Last updated: 4/21/2015

References
  1. Relapsing polychondritis. DermNet NZ. December 2013; http://www.dermnetnz.org/dermal-infiltrative/relapsing-polychondritis.html.
  2. Relapsing polychondritis. Orphanet. July 2014; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=728.
  3. Nicholas Compton, MD. Polychondritis. Medscape Reference. March 2015; http://emedicine.medscape.com/article/331475-overview.


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Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Relapsing polychondritis. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
  • Research studies involving relapsing polychondritis are ongoing through the Translational Research Program at the Virgina Mason Benaroya Research Institute in Seattle Washington. Click on the link above to learn more about these studies.
Other Names for this Disease
  • Chronic atrophic polychondritis
  • Recurrent polychondritis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.