Other Names for this Disease
- Syndrome of pseudomyxoma peritonei
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Pseudomyxoma peritonei is first treated with surgery to remove as much of the tumor as possible (debulking). Additional surgeries may be needed to remove more of the tumor if it is not completely removed during the first surgery. Chemotherapy is most often used to treat cancers that might spread to other parts of the body (metastasize). Though pseudomyxoma peritonei is extremely unlikely to metastasize, it has a high chance of regrowing after surgery if all tumor cells are not removed. As such, chemotherapy may be placed directly into the peritoneal cavity during surgery for pseudomyxoma peritonei to destroy any tumor cells that might remain but are too small to be seen in order to prevent the tumor from regrowing. Though the use of chemotherapy during surgery has not been compared directly with surgery alone, chemotherapy during surgery is considered the standard treatment for pseudomyxoma peritonei.
Last updated: 9/25/2011
- Sugarbaker PH. New standard of care for appendiceal epithelial neoplasms and pseudomyxoma peritonei syndrome?. Lancet Oncology. 2006; 7:69-76. http://www.ncbi.nlm.nih.gov/pubmed/16389186. Accessed 9/23/2011.
- Smeenk RM, Bruin SC, van Velthuysen ML, Verwaal VJ. Pseudomyxoma Peritonei. Current Problems in Surgery. 2008; 45:527-575. http://www.ncbi.nlm.nih.gov/pubmed/18590843. Accessed 9/21/2011.
- Yan TD, Black D, Savady R, Sugarbaker PH. A systematic review on the efficacy of cytoreductive surgery and perioperative intraperitoneal chemotherapy for pseudomyxoma peritonei. Annals of Surgical Oncology. 2007; 14:484-492. http://www.ncbi.nlm.nih.gov/pubmed/17054002. Accessed 9/21/2011.
- ClinicalTrials.gov lists trials that are studying or have studied Pseudomyxoma peritonei. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.