Other Names for this Disease
- Renal glucosuria
- Familial renal glucosuria
- SGLT2 deficiency
glucose is excreted in the urine despite normal or low blood glucose levels. With normal kidney function, glucose is excreted in the urine only when there are abnormally elevated levels of glucose in the blood. However, in people with renal glycosuria, glucose is abnormally eliminated in the urine due to improper functioning of the renal tubules, which are the primary components of the filtering units of the kidneys. In most people with renal glycosuria, there are no apparent symptoms or serious effects. Rare cases of polyuria (increased urine output), enuresis (involuntary urination), and mild growth and pubertal maturational delay have been reported. When renal glycosuria occurs as an isolated finding with otherwise normal kidney function, the condition is thought to be inherited in an autosomal recessive manner, caused by mutations in the SLC5A2 gene. Treatment is not typically needed.Renal glycosuria is a rare condition in which
Last updated: 1/20/2016
- Renal glycosuria. National Organization for Rare Disorders (NORD). 2007; http://rarediseases.org/rare-diseases/renal-glycosuria/.
- Rajendra Bhimma. Renal Glycosuria. Medscape. 5/2/2015; http://emedicine.medscape.com/article/983678-overview.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
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- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
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