Autoimmune polyglandular syndrome type 2
Other Names for this Disease
- Diabetes mellitus, Addison's disease, myxedema
- Multiple endocrine deficiency syndrome, type 2
- Polyglandular autoimmune syndrome, type 2
- Autoimmune polyendocrine syndrome type 2
- Schmidt syndrome
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autoimmune disorder that affects many hormone-producing (endocrine) glands. This condition is characterized by the presence of Addison's disease along with autoimmune thyroid disease and/or type 1 diabetes. Affected individuals may also have problems with other endocrine glands. Autoimmune polyglandular syndrome type 2 is diagnosed in adulthood, typically around age 30. This condition occurs more often in women than men, and treatment primarily involves hormone replacement therapy. The cause of autoimmune polyglandular syndrome type 2 is unknown, although it may involve a combination of genetic and environmental factors.Autoimmune polyglandular syndrome type 2 is an
Last updated: 12/28/2015
- Sivarajah S. Polyglandular Autoimmune Syndrome, Type II. Medscape Reference. August 28, 2014; http://emedicine.medscape.com/article/124287-overview. Accessed 12/28/2015.
- Barker JM. Polyglandular Deficiency Syndromes. Merck Manual for Healthcare Professionals. January 2014; http://www.merckmanuals.com/professional/endocrine-and-metabolic-disorders/polyglandular-deficiency-syndromes/polyglandular-deficiency-syndromes. Accessed 12/28/2015.
- The Merck Manuals Online Medical Library provides information on this condition for patients and caregivers.
- The National Endocrine and Metabolic Diseases Information Service, a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), provides information on this topic. Click on the link to view the information on this topic.
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Autoimmune polyglandular syndrome type 2. Click on the link to view a sample search on this topic.