- Erythema multiforme major
Your QuestionI have a friend whose grandson recently died from complications associated with Stevens-Johnson syndrome. I have not been able to find information about this condition. What information can you provide?
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Questions on this page
- What is Stevens-Johnson syndrome?
- What are the signs and symptoms of Stevens-Johnson syndrome?
- What causes Stevens-Johnson syndrome?
- What complications may be associated with Stevens-Johnson syndrome?
- How might Stevens-Johnson syndrome be treated?
- What is the prognosis for individuals with Stevens-Johnson syndrome?
Possible complications of Stevens-Johnson syndrome include:
- Secondary skin infections (cellulitis) - which can lead to life-threatening complications like meningitis and sepsis
- Sepsis - which occurs when bacteria from an infection enters the bloodstream and spreads throughout the body, possibly leading to shock and organ failure
- Eye Problems - which may include extensive tissue damage and scarring which may result in blindness
- Damage to internal organs - which may involve the lungs, heart, kidney and liver
- Permanent skin damage - which may include abnormal bumps and pigmentation as well as hair loss and abnormal growth of the finger and toe nails
Treatment of severe symptoms may include:
- Antibiotics to control any skin infections
- Corticosteroids to control inflammation
- Intravenous immunoglobulins (IVIG) to stop the disease process
Treatment for the eye may include artificial tears, antibiotics, or corticosteroids.
- Facts About The Cornea and Corneal Disease. National Eye Institute (NEI). May 2013; http://www.nei.nih.gov/health/cornealdisease/#m. Accessed 7/8/2015.
- Roujeau JC. Stevens-Johnson syndrome. Orphanet. 2009; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=36426. Accessed 3/15/2010.
- Stevens-Johnson syndrome. MayoClinic.com. April 22, 2014; http://www.mayoclinic.com/health/stevens-johnson-syndrome/DS00940/METHOD=print. Accessed 7/8/2015.
- Zieve D, Eltz DR. Erythema multiforme. MedlinePlus. 2010; http://www.nlm.nih.gov/medlineplus/ency/article/000851.htm. Accessed 3/15/2010.