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Diseases

Genetic and Rare Diseases Information Center (GARD)

Sydenham's chorea


Other Names for this Disease
  • St. Vitus dance
  • Sydenham chorea
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Overview

Sydenham's chorea is a neurological disorder characterized by rapid, jerky, irregular, and involuntary movements (chorea), especially of the face and limbs.[1][2] Additional symptoms may include muscle weakness, slurred speech, headaches, and seizures. Children with Sydenham's chorea often have emotional or behavioral problems such as obsessive-compulsive disorder, distractibility, irritability, and inappropriate outbursts of laughing or crying.[2] Sydenham's chorea mostly affects children and adolescents and usually follows a Streptococcal infection by anywhere form 1-8 months.[1][2] Sydenham's chorea is one of the major clinical signs of acute rheumatic fever.[2]  The uncontrolled movements are often worse during periods of stress, fatigue, or excitement. In some cases, only one side of the body is affected. Sydenham's chorea usually resolves within 3 weeks to 3 months. However, symptoms may last longer in some cases.[1]
Last updated: 7/9/2015

References

  1. Okun, Michael. Sydenham Chorea. National Organization for Rare Disorders (NORD). 2010; https://rarediseases.org/rare-diseases/sydenham-chorea/. Accessed 7/9/2015.
  2. Cruse, Robert. Sydenham chorea. UpToDate. April 29, 2014; http://www.uptodate.com/contents/sydenham-chorea. Accessed 7/9/2015.
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In Depth Information

  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Sydenham's chorea. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • St. Vitus dance
  • Sydenham chorea
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.