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Diseases

Genetic and Rare Diseases Information Center (GARD)

Sydenham's chorea


Other Names for this Disease
  • DYT21
  • Primary dystonia, DYT21 type
  • St. Vitus dance
  • Sydenham chorea
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Overview

Sydenham's chorea is a neurological disorder characterized by rapid, jerky, irregular, and involuntary movements (chorea), especially of the face and limbs.[1][2] Additional symptoms may include muscle weakness, slurred speech, headaches, and seizures. Children with Sydenham's chorea often have emotional or behavioral problems such as obsessive-compulsive disorder, distractibility, irritability, and inappropriate outbursts of laughing or crying.[2] Sydenham's chorea mostly affects children and adolescents and usually follows a Streptococcal infection by anywhere form 1-8 months.[1][2] Sydenham's chorea is one of the major clinical signs of acute rheumatic fever.[2]  The uncontrolled movements are often worse during periods of stress, fatigue, or excitement. In some cases, only one side of the body is affected. Sydenham's chorea usually resolves within 3 weeks to 3 months. However, symptoms may last longer in some cases.[1]
Last updated: 7/9/2015

References

  1. Okun, Michael. Sydenham Chorea. National Organization for Rare Disorders (NORD). 2010; https://rarediseases.org/rare-diseases/sydenham-chorea/. Accessed 7/9/2015.
  2. Cruse, Robert. Sydenham chorea. UpToDate. April 29, 2014; http://www.uptodate.com/contents/sydenham-chorea. Accessed 7/9/2015.
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In Depth Information

  • PubMed is a searchable database of medical literature and lists journal articles that discuss Sydenham's chorea. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • DYT21
  • Primary dystonia, DYT21 type
  • St. Vitus dance
  • Sydenham chorea
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.