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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Sydenham's chorea


Other Names for this Disease
  • DYT21
  • Primary dystonia, DYT21 type
  • St. Vitus dance
  • Sydenham chorea
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Treatment

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How might Sydenham's chorea be treated?

In most cases, patients with Sydenham's chorea recover fully with no treatment.[1] Drugs that have been used to treat patients with significant movement problems include corticosteroids, valproic acid, diazepam, chlorpromazine, and carbamazepine. In patients who do not respond to these drugs, haloperidol or pimozide may be used.[1] In addition, patients with Sydenham's chorea are usually treated with antibiotics to prevent another Streptococcal infection and to minimize the risk of rheumatic heart disease.[1] Sydenham's chorea usually resolves within 12-15 months, though symptoms may persist for two years or more. Up to 30% of patients experience a recurrence of Sydenham's chorea within a few years. Some believe that treatment with an antibiotic reduces the risk of recurrence.[1]
Last updated: 7/10/2015

References
  1. Cruse, Robert. Sydenham chorea. UpToDate. April 29, 2014; http://www.uptodate.com/contents/sydenham-chorea. Accessed 7/10/2015.


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Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Sydenham's chorea. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Other Names for this Disease
  • DYT21
  • Primary dystonia, DYT21 type
  • St. Vitus dance
  • Sydenham chorea
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.