Transposition of the great arteries
Other Names for this Disease
- Dextro-looped transposition of the great arteries
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congenital heart defect in which there is a reversal of the normal connections of the aorta and the pulmonary artery with the heart. The aorta and pulmonary artery are reversed, which causes oxygen-poor blood to be circulated to the body and oxygen-rich blood to be circulated between the lungs and the heart, rather than to the body. Symptoms are apparent at birth and include great difficulty breathing and severe cyanosis (a bluish discoloration of the skin). The exact cause of TGA in most cases is unknown. Surgery is done to correct the abnormality during the first few days of life.Transposition of the great arteries (TGA) is a type of
Last updated: 6/27/2011
- Gregory S. Liptak. Transposition of the Great Arteries. Merck Manuals. April 2006; http://www.merckmanuals.com/home/sec23/ch265/ch265b.html#sec23-ch265-ch265b-306. Accessed 6/27/2011.
- Paula Martins and Eduardo Castela. Transposition of the great arteries. Orphanet Journal of Rarer Diseases. October 2008; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577629/?tool=pubmed. Accessed 6/27/2011.
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- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
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