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Diseases

Genetic and Rare Diseases Information Center (GARD)

Urachal cancer


Other Names for this Disease
  • Urachal carcinoma
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Treatment

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How might urachal cancer be treated?

Surgical resection in the form of partial (segmental) or radical cystoprostatectomy is the main form of treatment.[1] However, similar results are seen with a conservative surgery that involves partial cystectomy with umbilicotomy and removal of the urachus.[1][2] The role of chemotherapy and radiation therapy for the treatment of urachal cancer is unclear, although some studies show that chemotherapy can induce objective response in some cases.[1] Chemotherapy regimens that may be used include: single-agent 5-fluorouracil (5-FU), 5-FU and cisplatin, 5-FU, lomustine and vincristine, taxol and cisplatin, platinum and etoposide, and MVAC (methotrexate, vinblastine, doxorubicin, cisplatin) alone or in conjunction with radiation therapy.[1] 
Last updated: 12/16/2009

References
  1. Molina JR, Quevedo JF, Furth AF, Richardson RL, Zincke H, Burch PA. 2007; http://onlinelibrary.wiley.com/doi/10.1002/cncr.23070/full. Accessed 12/16/2009.
  2. Jankowski JT, Cherullo EE, Steinway ML, Feng AH. Cystectomy, Partial. eMedicine. 2008; http://emedicine.medscape.com/article/446101-overview. Accessed 12/16/2009.


GARD Video Tutorial

  • Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.

    Finding Treatment Information

Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Urachal cancer. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Other Names for this Disease
  • Urachal carcinoma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.