Other Names for this Disease
- VKH syndrome
- Vogt-Koyanagi-Harada syndrome
- Uveomenigitic syndrome
- VKH disease
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Your QuestionWhat is the cause of Vogt-Koyanagi-Harada syndrome?
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The exact cause of Vogt-Koyanagi-Harada (VKH) disease is not well understood, but research suggests it is an autoimmune disease in which the body attacks its own pigment cells (melanocytes), possibly in response to an infection (such as a virus). The strong association between VKH disease and certain ethnic groups suggests that genetic factors may be involved. Genes related to the immune system, namely those genes in the HLA gene family, may play a role in the development of VKH disease.
Last updated: 1/8/2015
- Fang W, Yang P.. Vogt-Koyanagi-Harada. Current Eye Research. May, 2008; Accessed 10/28/2010.
- Walton RC.. Vogt-Koyanagi-Harada Disease. Emedicine. April 14, 2010; http://emedicine.medscape.com/article/1229432-overview. Accessed 10/28/2010.