Neurofibromatosis type 1
Other Names for this Disease
- Recklinghausen's disease
- Type 1 neurofibromatosis
- Von Recklinghausen disease
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Your QuestionI have neurofibromatosis type 1, and in the last couple of years I have developed severe skin itching. Do you think the itching has anything to do with NF1?
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Skin itching, or pruritus, can be a symptom of neurofibromatosis type 1. Neurofibromas under the skin can be very itchy, especially when they are growing. This intense itchiness may interfere with sleep and other daily activities. A type of antihistamine medication called ketotifen has been effective in treating this symptom.
Last updated: 7/20/2015
- Riccardi VM. The genetic predisposition to and histogenesis of neurofibromas and neurofibrosarcoma in neurofibromatosis type 1. Neurosurg Focus. June 2007; 22(6):E3.
- Riccardi VM. A controlled multiphase trial of ketotifen to minimize neurofibroma-associated pain and itching. Arch Dermatol. May 1993; 129(5):587-581.