Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Nodular nonsuppurative panniculitis


Other Names for this Disease
  • Weber Christian disease
  • Weber-Christian disease
  • Panniculitis nodular nonsuppurative
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

Newline Maker

How might nodular nonsuppurative panniculitis be treated?

Treatment for nodular nonsuppurative panniculitis (NNP) generally aims at controlling and relieving the symptoms that an individual has. Before treatment is initiated, a work-up should be completed to determine whether the condition is secondary to another underlying disorder. If there is an underlying disorder, treatment of this disorder may relieve the symptoms of NNP. In some cases, skin lesions heal spontaneously (remission) but the lesions often later return.[1] There is no treatment method found to be effective for all individuals with NNP. Medications used to treat the condition may include systemic steroids (such as prednisone) to suppress sudden attacks; nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce fever and other signs of malaise; and/or immunosuppressive drugs.[2][3] Relief of symptoms in some affected individuals has also been reported with fibrinolytic agents (medications that help prevent blood clots), hydroxychloroquine, azathioprine, thalidomide, cyclophosphamide, tetracycline, cyclosporin, mycophenolate, and clofazimine.[2][3]

More detailed information about the management of nodular nonsuppurative panniculitis is available on the Treatment and Medication sections of the Medscape Reference Web site.
Last updated: 4/6/2016

References
  1. Panniculitis, Idiopathic Nodular. NORD. July 23, 2007; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/297/viewAbstract. Accessed 4/6/2016.
  2. Nodular non-suppurative panniculitis. Orphanet. March 2007; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=33577. Accessed 4/6/2016.
  3. Eyal Muscal. Weber-Christian Disease. Medscape Reference. Jan 22, 2015; http://emedicine.medscape.com/article/1008411-overview.


Other Names for this Disease
  • Weber Christian disease
  • Weber-Christian disease
  • Panniculitis nodular nonsuppurative
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.