- Xeroderma pigmentosa
Your QuestionIt there a cure for xeroderma pigmentosum? If there's no cure, can it at least be treated?
We have identified the following information that we hope you find helpful. If you still have questions, please contact us.
Questions on this page
- Protection from ultraviolet light
- Frequent skin and eye examinations
- Prompt removal of cancerous tissue
- Neurological examination
- Psychosocial care
Small, premalignant skin lesions such as actinic keratoses can be treated with topical 5-fluorouracil or frozen with liquid nitrogen. Larger areas of skin involvement may be treated with dermatome shaving or dermabrasion to remove damaged superficial epidermal layers. Skin cancers can be treated with electrodesiccation and curettage (scrapes away the lesion and uses electricity to kill any remaining cells), surgical excision, or chemosurgery. High dose oral isotretinoin can be used to prevent new cancers. Cancers of the eyelids, conjunctiva, and cornea should be treated surgically. Corneal transplantation may be necessary for those with severe keratitis and corneal opacity.
More detailed information about the treatment of XP may be accessed through the following online resources:
- Xeroderma pigmentosum. Genetics Home Reference (GHR). 2010; http://ghr.nlm.nih.gov/condition/xeroderma-pigmentosum. Accessed 10/21/2010.
- Understanding Xeroderma Pigmentosum. NIH Clinical Center. 2006; http://www.cc.nih.gov/ccc/patient_education/pepubs/xp7_17.pdf. Accessed 10/21/2010.
- Kenneth H Kraemer. Xeroderma Pigmentosum. GeneReviews. 2008; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=xp. Accessed 10/21/2010.