Other Names for this Disease
- Keratoderma, Palmoplantar
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Treatment of both hereditary and nonhereditary palmoplantar keratodermas is difficult. Treatment usually only results in short-term improvement and often has adverse side effects. The goal of treatment is usually to soften the thickened skin and makes it less noticeable. Treatment may include simple measures such as saltwater soaks, emollients, and paring. More aggressive treatment includes topical keratolytics, topical retinoids, systemic retinoids (acitretin), topical vitamin D ointment (calcipotriol), or surgery to removed the skin, following by skin grafting.
Last updated: 4/29/2011
- Lee RA & Elston DM. Keratosis Palmaris et Plantaris. eMedicine. July 2008; http://emedicine.medscape.com/article/1108406-overview#a1. Accessed 4/29/2011.
- Palmoplantar keratoderma. DermNet. November 18, 2014; http://www.dermnet.org.nz/scaly/palmoplantar-keratoderma.html. Accessed 4/29/2011.
- Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.
- ClinicalTrials.gov lists trials that are studying or have studied Palmoplantar keratoderma. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.