Other Names for this Disease
- Idiopathic sclerosing mesenteritis
- Isolated mesenteric lipodystrophy
- Lipomatous mesenteritis
- Liposclerotic mesenteritis
- Mesenteric fibromatosis
Treatment for sclerosing mesenteritis is most often based on the stage of the disease.
- In the early stage when fat necrosis predominates, many physicians tend not to treat because the disease process may regress spontaneously.
- When chronic inflammation becomes a prominent feature but fibrosis is not yet fully developed, medical treatment with corticosteroids, colchicine, immunosuppressants, or orally administered progesterone may be beneficial in the prevention of disease progression. These medications are only given for a short period since they can cause serious side effects. Some studies have shown that patients with sclerosing mesenteritis may benefit from a drug combination of tamoxifen and prednisone.
- When fibrosis becomes extensive, especially when the disease presents as a large fibrotic mass with bowel obstruction, surgical interventions may be necessary.
Last updated: 10/1/2015
- Sclerosing Mesenteritis. The Doctor's Doctor Web site. 2002; http://www.thedoctorsdoctor.com/diseases/sclerosing_mesenteritis.htm. Accessed 10/1/2015.
- Ehrenpreis ED, Deepak P. Sclerosing mesenteritis. National Organization for Rare Disorders (NORD). 2011; http://rarediseases.org/rare-diseases/sclerosing-mesenteritis/. Accessed 10/1/2015.
- Sclerosing mesenteritis. MayoClinic.org. March 22, 2014; http://www.mayoclinic.org/diseases-conditions/sclerosing-mesenteritis/basics/definition/con-20037148. Accessed 10/1/2015.
- Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.