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Diseases

Genetic and Rare Diseases Information Center (GARD)

Henoch-Schonlein purpura


Other Names for this Disease
  • Purpura, Schonlein-Henoch
  • Anaphylactoid purpura
  • Vascular purpura
  • Henoch Schonlein purpura
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Henoch-Schonlein purpura (HSP) is a disease that involves purple spots on the skin (purpura), joint pain, digestive problems, and glomerulonephritis (a type of kidney disorder).[1] While the cause of this condition is not fully understood, it may develop as an immune response to an infection.[1][2] HSP is usually seen in children, but it may affect people of any age.[2] Most cases go away on their own without treatment.[1] For those cases which require treatment, the main goal is to relieve symptoms such as joint pain, abdominal pain, or swelling. In many cases, over-the-counter medicines can be used. In some patients with severe arthritis, prednisone, a steroid medicine, may be prescribed.[1][2]
Last updated: 4/14/2013

References

  1. Borigini MJ. Henoch-Schonlein purpura. MedlinePlus. 2011; http://www.nlm.nih.gov/medlineplus/ency/article/000425.htm. Accessed 4/12/2013.
  2. Henoch-Schonlein Purpura. The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC). September 2012; http://kidney.niddk.nih.gov/kudiseases/pubs/HSP/. Accessed 4/12/2013.
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Basic Information

  • The American Academy of Family Physicians provides a basic overview of Henoch-Schonlein purpura.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC), part of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), conducts and supports research on a broad spectrum of diseases affecting public health. Click on the link to view information on this topic.
  • The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Henoch-Schonlein purpura. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Purpura, Schonlein-Henoch
  • Anaphylactoid purpura
  • Vascular purpura
  • Henoch Schonlein purpura
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.