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Diseases

Genetic and Rare Diseases Information Center (GARD)

Lafora disease


Other Names for this Disease
  • Lafora body disorder
  • Epilepsy progressive myoclonic 2
  • EPM2
  • Myoclonic epilepsy of Lafora
  • MELF
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Your Question

Is a ketogenic diet known to help individuals with Lafora disease?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

Is a ketogenic diet known to help people with Lafora disease (LD)?

The impact of a long-term ketogenic diet was studied in five people with Lafora disease. Although the diet was well-tolerated by patients, it did not stop disease progression or improve symptoms. However, given the small study population, the researchers could not exclude the possibility that a ketogenic diet has the potential to slow down the disease progression. Larger studies are needed to evaluate the impact of a ketogenic diet in treating patients with Lafora disease.[1]
Last updated: 9/29/2015

References
  • Cardinali S, Canafoglia L, Bertoli S, Franceschetti S, Lanzi G, Tagliabue A, Veggiotti P. A pilot study of a ketogenic diet in patients with Lafora body disease. Epilepsy Res. 2006; 69(2):129-34. http://www.ncbi.nlm.nih.gov/pubmed/16504479. Accessed 4/12/2012.
Other Names for this Disease
  • Lafora body disorder
  • Epilepsy progressive myoclonic 2
  • EPM2
  • Myoclonic epilepsy of Lafora
  • MELF
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.