Other Names for this Disease
- Mediastinal fibrosis
- Idiopathic mediastinal fibrosis
- Sclerosing mediastinitis
- IgG4-related mediastinitis
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There is no cure for fibrosing mediastinitis and the benefits of current treatments are unclear. In general, treatment options depend on which structures of the mediastinum are affected (i.e. the heart, large blood vessels, windpipe, esophagus, and lymph nodes), the severity of the scarring and, in some cases, the cause of the condition. For example, fibrosing mediastinitis caused by histoplasmosis may be treated with antifungal medications while cases caused by autoimmune disorders may respond best to corticosteroids. Other treatment options include surgery to removed scarred tissue and local therapies to treat specific problems (i.e. stents, laser therapy).
Last updated: 11/6/2014
- Steven E Weinberger, MD. Fibrosing Mediastinitis. UpToDate. Aug 06, 2013; http://www.uptodate.com/contents/fibrosing-mediastinitis. Accessed 11/5/2014.
- Rossi S, McAdams H, Rosado-de-Christenson M, Franks T, Galvin J. Fibrosing Mediastinitis. Radiographics. 2001; 21(3):737-757. Accessed 11/5/2014.
- L. Joseph Wheat, Alison G. Freifeld, Martin B. Kleiman, John W. Baddley, David S. McKinsey, James E. Loyd. Clinical Practice Guidelines for the Management of Patients with Histoplasmosis: 2007 Update by the Infectious Diseases Society of America. Clinical Infectious Disease. October, 2007; 45:807-825. http://www.idsociety.org/uploadedFiles/IDSA/Guidelines-Patient_Care/PDF_Library/Histoplasmosis.pdf#search=%22Mediastinal fibrosis%22. Accessed 11/3/2014.