Peters plus syndrome
- Peters anomaly with short limb dwarfism
- Krause-Kivlin syndrome
- Krause-van Schooneveld-Kivlin syndrome
- Congenital disorder of glycosylation with developmental anomaly
Your QuestionMy daughter has Peters plus syndrome since birth. She has had multiple surgeries for glaucoma. It is very difficult to find information on her condition as well as finding out more information that will benefit her future. Can you tell me if she will be able to have children? Will she have a normal life span? I had another child with Peters plus syndrome who passed away at birth. I never found out why this happened to my children. What did I do wrong? Or did I? Please help me find these answers.
We have identified the following information that we hope you find helpful. If you still have questions, please contact us.
Questions on this page
- What is Peters plus syndrome?
- What are the signs and symptoms of Peters plus syndrome?
- What treatment is available for Peters plus syndrome?
- Can people with Peters plus syndrome have children?
- Does Peters plus syndrome affect a person's lifespan?
- What causes Peters plus syndrome?
- Is there anything that I might have done that could have caused or prevented Peters plus syndrome?
- How can I find a genetics professional in my area?
- Eye involvement: anomalies of the anterior chamber of the eye (e.g. Peters' anomaly); glaucoma; cataract
- Short stature
- Developmental delay
- Characteristic facial features (e.g. cleft lip and plate)
- Other associated findings (e.g congenital heart defects; anomalies of the kidney; structural brain malformations; congenital hypothyroidism; conductive hearing loss)
Treatment varies from person to person and is based on the extent of the disease. Once a person has been diagnosed with Peters plus syndrome, the following evaluations are recommended :
- Eye examination
- Growth hormone testing
- Developmental assessment
- Heart examination
- Kidney examination
- Head examination
- Thyroid testing
- Hearing assessment
Assessment by a ophthalmologist every three months or as indicated is recommended as well as regular developmental assessments.
Agents, like corticosteroids, should be avoided, as they increase the risk of glaucoma.
The following online resources can help you find a genetics professional in your community:
- The National Society of Genetic Counselors provides a searchable directory of US and international genetic counseling services.
- The American College of Medical Genetics has a searchable database of US genetics clinics.
- The University of Kansas Medical Center provides a list of US and international genetic centers, clinics, and departments.
- The American Society of Human Genetics maintains a database of its members, which includes individuals who live outside of the United States. Visit the link to obtain a list of the geneticists in your country, some of whom may be researchers that do not provide medical care.
- Peters plus syndrome. Genetics Home Reference. March 2008; http://ghr.nlm.nih.gov/condition=petersplussyndrome. Accessed 3/9/2008.
- Peters Plus Syndrome. GeneReviews. October 8, 2007; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=peters-plus. Accessed 3/9/2009.