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Genetic and Rare Diseases Information Center (GARD)

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Behcet's disease


Other Names for this Disease
  • BD
  • Behcet disease
  • Behçet disease
  • Behcet syndrome
  • Behcet's syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Behcet's disease is a chronic multisystem inflammatory disorder characterized by ulcers affecting the mouth and genitals, various skin lesions, and abnormalities affecting the eyes. In some people, the disease also results in arthritis (swollen, painful, stiff joints), skin problems, and inflammation of the digestive tract, brain, and spinal cord.[1][2][3] Although it can happen at any age, symptoms generally begin when individuals are in their 20s or 30s. The disease is common in Japan, Turkey and Israel, and less common in the United States.[2] The exact cause of Behcet's disease is still unknown.[1][2][3]  Treatment is symptomatic and supportive.Experience is evolving with the use of interferon-alpha and with agents which inhibit tumor necrosis factor (TNF) in the treatment of Behçet’s disease. Behcet's disease is a lifelong disorder that comes and goes. Spontaneous remission over time is common for individuals with Behçet’s syndrome but permanent remission of symptoms has not been reported.[1][2]
Last updated: 5/25/2015

References

  1. Calamia KT. Behcet's Syndrome. National Organization for Rare Disorders (NORD). April 28, 2015; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/100/viewAbstract. Accessed 5/25/2015.
  2. NINDS Behcet's Disease Information Page. National Institute of Neurological Disorders and Stroke (NINDS). February 6, 2012; http://www.ninds.nih.gov/disorders/behcet/behcet.htm. Accessed 5/25/2015.
  3. Questions and Answers about Behçet’s Disease. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). April 2012; http://www.niams.nih.gov/Health_Info/Behcets_Disease/default.asp. Accessed 5/25/2015.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

2 question(s) from the public on Behcet's disease have been answered. See questions and answers . You can also submit a new question.

Basic Information

  • The Johns Hopkins Vasculitis Center website provides information about different types of vasculitis. Click on the link to access information about Behcet's disease.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Eye Institute (NEI) was established by Congress in 1968 to protect and prolong the vision of the American people. Click on the link to view information on this topic. 
  • The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) support research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases, the training of basic and clinical scientists to carry out this research, and the dissemination of information on research progress in these diseases. Click on the link to view information on this topic.
  • The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Behcet's disease. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • BD
  • Behcet disease
  • Behçet disease
  • Behcet syndrome
  • Behcet's syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.