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Diseases

Genetic and Rare Diseases Information Center (GARD)

HELLP syndrome


Other Names for this Disease
  • Hemolysis, Elevated Liver Enzymes, Lowered Platelets
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Overview

HELLP syndrome is a rare but serious illness in pregnancy. This condition can start quickly, most often in the last 3 months of pregnancy (the third trimester). It can also start soon after the baby is delivered.[1] HELLP stands for Hemolysis, Elevated Liver enzyme levels and a Low Platelet count. These problems are often found in women with this syndrome.[1][2] These problems, along with the high blood pressure commonly found in association with HELLP syndrome, can lead to problems for both the mother and the baby.[1] Many cases of HELLP syndrome are associated with  preeclampsia or eclampsia.[2] The exact cause of HELLP syndrome remains unknown, making it difficult to determine which women will be affected.[1] The main treatment is to deliver the baby as soon as possible. In some cases, medicines are prescribed.[2]   
Last updated: 2/23/2016

References

  1. HELLP Syndrome. FamilyDoctor.org. April 2014; http://familydoctor.org/familydoctor/en/diseases-conditions/hellp-syndrome.printerview.all.html.
  2. White CD. HELLP syndrome. MedlinePlus. November 2014; http://www.nlm.nih.gov/medlineplus/ency/article/000890.htm.
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Basic Information

  • The American Pregnancy Association provides information about HELLP syndrome.
  • FamilyDoctor.org provides additional information about HELLP syndrome. Click on the link above to access this information.
  • March of Dimes has information on HELLP syndrome.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The Merck Manual provides information on this condition for patients and caregivers. 
  • The Preeclampsia Foundation provides information about HELLP syndrome. The information includes the signs and symptoms of the syndrome, risks, prognosis, and more. 

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • PubMed is a searchable database of medical literature and lists journal articles that discuss HELLP syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Hemolysis, Elevated Liver Enzymes, Lowered Platelets
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.