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Diseases

Genetic and Rare Diseases Information Center (GARD)

Morgagni-Stewart-Morel syndrome


Other Names for this Disease
  • MSM syndrome
  • Hyperostosis frontalis interna, obesity, shortness and cognitive impairment
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Treatment

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How might hyperostosis frontalis interna be treated?

Unfortunately, there is currently no known standard treatment for hyperostosis frontalis interna (HFI). Seizures and headaches that may be associated with HFI are typically treated with standard medications.[1]

There is little published, accessible information regarding treatment options for HFI. In one journal article, the authors discuss an individual with Morgagni-Stewart-Morel syndrome who reportedly had violent headaches. They stated that surgery was performed to remove the hypertrophic frontal bone, followed by dura and bone reconstruction. The authors stated that the pains ceased immediately after the operation. They further discuss surgical treatment, especially in cases with high intensity headaches.[2]
Last updated: 3/28/2011

References
  1. Hyperostosis Frontalis Interna. NORD. 2007; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Hyperostosis%20Frontalis%20Interna. Accessed 3/28/2011.
  2. Latka D, Szydlik W, Glaubic-Latka M, Mrówka R. [A case of Morgagni-Morel-Stewart syndrome with violent headaches predominant in the clinical course treated surgically]. Neurologia i Neurochirurgia Polska. March-April 1995; 29(2):253-256. http://www.ncbi.nlm.nih.gov/pubmed/7651598. Accessed 3/27/2011.


GARD Video Tutorial

  • Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.

    Finding Treatment Information

Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists a trial entitled 'Evaluation and Treatment of Skeletal Diseases.' Click on ClinicalTrials.gov to learn more.
Other Names for this Disease
  • MSM syndrome
  • Hyperostosis frontalis interna, obesity, shortness and cognitive impairment
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.