Other Names for this Disease
- Acquired angioneurotic edema
- Acquired bradykinine-induced angioedema
- Acquired C1 inhibitor deficiency
- Acquired non histamine-induced angioedema
 Swelling episodes may be triggered by mild trauma (e.g., dental work), viral illness, cold exposure, pregnancy, ingestion of certain foods, or emotional stress. There are two forms of AAE: type I and type II. AAE type I is most commonly associated with B-cell lymphoproliferative disorders and consumption of C1-INH. AAE type II is an autoimmune condition associated with the presence of an autoantibody against C1-INH. Treatment aims to control episodes and normalize C1-INH levels. When possible, the underlying disorder should be treated.Acquired angioedema (AAE) is a rare condition characterized by recurrent episodes of swelling (edema). Affected people may have swelling of the face, lips, tongue, limbs, and genitals. Sometimes there is abdominal pain due to edema of the gastrointestinal mucosa, and life-threatening edema of the upper respiratory tract.
Last updated: 8/25/2014
- Ru'aa Al Harithy. Acquired Angioedema. Medscape Reference. July 31, 2014; http://emedicine.medscape.com/article/1048887-overview. Accessed 8/25/2014.
- Peter J. Delves. Hereditary and Acquired Angioedema. Merck Manuals. March, 2014; http://www.merckmanuals.com/professional/immunology_allergic_disorders/allergic_autoimmune_and_other_hypersensitivity_disorders/hereditary_and_acquired_angioedema.html. Accessed 8/25/2014.
- Laurence Bouillet. Acquired Angioedema. Orphanet. August, 2011; Accessed 8/25/2014.
- DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
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- The Merck Manual for health care professionals provides information on Acquired angioedema.
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