Other Names for this Disease
- Immunodeficiency with thymoma
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hypogammaglobulinemia and low levels of B cells along with a benign thymic tumor (thymoma) on chest X-ray. Symptoms include frequent opportunistic infections involving the sinuses and lungs, including severe CMV disease, P. carinii pneumonia, and mucocutaneous candidiasis. While the cause of Good syndrome remains unknown, there is some evidence that a defect of the bone marrow is involved. Treatment includes removal of the thymic tumor and immunoglobulin replacement.Good syndrome is a rare, adult-onset primary immunodeficiency suspected in patients who exhibit
Last updated: 10/31/2012
- Other Important Primary Immunodeficiency Diseases. Immune Deficiency Foundation. 2011; http://primaryimmune.org/about-primary-immunodeficiency-diseases/types-of-pidd/other-important-primary-immunodeficiency-diseases. Accessed 12/6/2011.
- Tarr PE, Sneller MC, Mechanic LJ, Economides A, Eger CM, Strober W, Cunningham-Rundles C, Lucey DR. Infections in patients with immunodeficiency with thymoma (Good syndrome). Report of 5 cases and review of the literature. Medicine (Baltimore). 2001; http://www.ncbi.nlm.nih.gov/pubmed/11307588. Accessed 12/6/2011.
- P Kelleher, SA Misbah. What is Good’s syndrome? Immunological abnormalities in patients with thymoma. J Clin Pathol . 2003; http://jcp.bmj.com/content/56/1/12.full. Accessed 12/6/2011.
On this page
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Good syndrome. Click on the link to view a sample search on this topic.