Other Names for this Disease
- Beta thalassemia intermedia
- Beta thalassemia major
- Beta thalassemia minor
- Beta-thalassemia intermedia
- Cooley's anemia
hemoglobin. Without sufficient hemoglobin, red blood cells do not develop normally, causing a shortage of mature red blood cells, leading to anemia and other health problems. Severe beta-thalassemia is called “thalassemia major” or “Cooley’s anemia.” Thalassemia intermedia is the less severe form. Mutations in the HBB gene cause beta-thalassemia. This condition is usually inherited in an autosomal recessive fashion, which means people with beta thalassemia have mutations in both of their HBB genes. People who have only one HBB mutation may have no symptoms or develop mild symptoms; these individuals are said to have thalassemia minor.Beta-thalassemia is a blood disorder that reduces the production of
Last updated: 7/7/2011
- Beta thalassemia. Genetics Home Reference. July 2009; http://ghr.nlm.nih.gov/condition/beta-thalassemia. Accessed 7/7/2011.
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