Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Central pontine myelinolysis

*

* Not a rare disease

Other Names for this Disease
  • CPM
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

Newline Maker

What treatments are available for central pontine myelinolysis?

Unfortunately, there is no treatment of choice for central pontine myelinolysis.  Four treatments have been tried in a small number of patients with encouraging results; however, these are experimental and none has been proven effective by a clinical trial.  The four experimental treatments include plasmapheresis, which is a procedure that attempts to remove toxic substances from the blood; thyrotropin-releasing hormone (TRH), which may help damaged tissues in the brain by increasing the blood supply to these areas; corticosteriods, which are medications that may suppress potentially harmful immune responses; or immunoglobulin therapy, which is also thought to remove toxic substances from the blood. [1]  Supportive therapy to address the symptoms of this condition include physical therapies and rehabilitation.[2]
Last updated: 7/21/2011

References
  1. Lampl C, Yazdi K. Central pontine myelinolysis. European neurology. 2002; 47:3-10. http://www.ncbi.nlm.nih.gov/pubmed/11803185. Accessed 7/20/2011.
  2. Central Pontine Myelinolysis Information Page. The National Institute of Neurological Disorders and Stroke. September 22, 2010; http://www.ninds.nih.gov/disorders/central_pontine/central_pontine_myelinolysis.htm. Accessed 9/22/2010.


GARD Video Tutorial

  • Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.

    Finding Treatment Information
Other Names for this Disease
  • CPM
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.