Central pontine myelinolysis
* Not a rare disease
Other Names for this Disease
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Unfortunately, there is no treatment of choice for central pontine myelinolysis. Four treatments have been tried in a small number of patients with encouraging results; however, these are experimental and none has been proven effective by a clinical trial. The four experimental treatments include plasmapheresis, which is a procedure that attempts to remove toxic substances from the blood; thyrotropin-releasing hormone (TRH), which may help damaged tissues in the brain by increasing the blood supply to these areas; corticosteriods, which are medications that may suppress potentially harmful immune responses; or immunoglobulin therapy, which is also thought to remove toxic substances from the blood.  Supportive therapy to address the symptoms of this condition include physical therapies and rehabilitation.
Last updated: 7/21/2011
- Lampl C, Yazdi K. Central pontine myelinolysis. European neurology. 2002; 47:3-10. http://www.ncbi.nlm.nih.gov/pubmed/11803185. Accessed 7/20/2011.
- Central Pontine Myelinolysis Information Page. The National Institute of Neurological Disorders and Stroke. September 22, 2010; http://www.ninds.nih.gov/disorders/central_pontine/central_pontine_myelinolysis.htm. Accessed 9/22/2010.