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Genetic and Rare Diseases Information Center (GARD)

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Ocular cicatricial pemphigoid


Other Names for this Disease
  • Cicatricial pemphigoid, ocular
  • Pemphigoid, ocular cicatricial
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Overview

Ocular cicatricial pemphigoid (OCP) is a form of mucous membrane pemphigoid (a group of rare, chronic autoimmune disorders) that affects the eyes. In the early stages, people with OCP generally experience chronic or relapsing conjunctivitis that is often characterized by tearing, irritation, burning, and/or mucus drainage. If left untreated, OCP can progress to severe conjunctiva scarring and vision loss. Involvement of other mucosal sites and the skin may also occur in OCP. The exact underlying cause is currently unknown. The treatment of OCP aims to slow disease progression and prevent complications. This usually involves long-term use of medications called immunomodulators which help regulate or normalize the immune system.[1][2]
Last updated: 6/10/2015

References

  1. Stephen Foster, MD. Ocular cicatricial pemphigoid. UpToDate. December 2013; Accessed 6/10/2015.
  2. C Stephen Foster, MD, FACS, FACR, FAAO. Ophthalmologic Manifestations of Cicatricial Pemphigoid. Medscape Reference. March 2013; http://emedicine.medscape.com/article/1191261-overview.
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Basic Information

  • The Merck Manual provides information on this condition for patients and caregivers. 
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
  • The Ocular Immunology and Uveitis Foundation offers an information page about Ocular cicatricial pemphigoid. Please click on the link to access this resource.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • The Merck Manual for health care professionals provides information on Ocular cicatricial pemphigoid.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Ocular cicatricial pemphigoid. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Cicatricial pemphigoid, ocular
  • Pemphigoid, ocular cicatricial
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.