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Diseases

Genetic and Rare Diseases Information Center (GARD)

Idiopathic inflammatory myopathy


Other Names for this Disease
  • Idiopathic inflammatory myopathy, familial
  • IIM
  • Myositis
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Overview

Idiopathic inflammatory myopathy refers to a group of conditions that affect the skeletal muscles (muscles used for movement). Although the condition can be diagnosed at any age, idiopathic inflammatory myopathy most commonly occurs in adults between ages 40 and 60 years or in children between ages 5 and 15 years. Signs and symptoms of the condition include muscle weakness, joint pain and fatigue. There are several forms of idiopathic inflammatory myopathy, including polymyositis, dermatomyositis, and sporadic inclusion body myositis, which are each associated with unique features.[1][2][3] As the name suggests, the cause of the condition is currently unknown (idiopathic). However, researchers suspect that it may occur due to a combination of genetic and environmental factors.[1] Treatment is supportive and based on the signs and symptoms present in each person.[3][2]
Last updated: 2/17/2016

References

  1. Idiopathic inflammatory myopathy. Genetics Home Reference. February 2011; http://ghr.nlm.nih.gov/condition/idiopathic-inflammatory-myopathy.
  2. Facts about Inflammatory Myopathies. Muscular Dystrophy Association. 2009; https://www.mda.org/sites/default/files/publications/Facts_Inflamm_Myopathies_P-199.pdf.
  3. Inflammatory Myopathies Fact Sheet. National Institute of Neurological Disorders and Stroke. July 2015; http://www.ninds.nih.gov/disorders/inflammatory_myopathies/detail_inflammatory_myopathies.htm.
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Basic Information

In Depth Information

  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Idiopathic inflammatory myopathy. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Idiopathic inflammatory myopathy, familial
  • IIM
  • Myositis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.