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Diseases

Genetic and Rare Diseases Information Center (GARD)

Autoimmune progesterone dermatitis


Other Names for this Disease
  • APD
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

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How might autoimmune progesterone dermatitis be treated?

Treatment for autoimmune progesterone dermatitis (APD) varies based on the severity of the condition. For example, mild skin problems such as eczema or hives may improve with topical steroids or oral antihistamines, respectively. More severe skin problems may require treatment with systemic corticosteroids.[1]

APD can also be treated with medications that suppress the body's production of progesterone. This is often accomplished with hormone-based therapies, such as estrogen, estradiol, tamoxifen, and/or danazol. Medications containing any progesterone (such as oral contraceptives) should be avoided.[1][2][3]

If other treatments are ineffective, surgical removal of the ovaries (oophorectomy) has been shown to cure the condition.[1][2][3]
Last updated: 4/16/2015

References
  1. Autoimmune progesterone dermatitis. DermNet NZ. December 2013; http://dermnetnz.org/reactions/progesterone-dermatitis.html.
  2. Tami Maguire. Autoimmune Progesterone Dermatitis. Dermatology Nursing. 2009; 21(4):190-192. http://www.medscape.com/viewarticle/712365. Accessed 1/9/2012.
  3. George R, Badawy SZ. Autoimmune progesterone dermatitis: a case report. Case Rep Obstet Gynecol. 2012; Epub 2012 Aug 9:


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Other Names for this Disease
  • APD
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.