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Diseases

Genetic and Rare Diseases Information Center (GARD)

Eosinophilic enteropathy


Other Names for this Disease
  • Eosinophilic gastroenteritis
  • Eosinophilic gastritis
  • Eosinophilic enteritis
  • Eosinophilic gastroenteropathy
  • Eosinophilic esophagitis
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Overview

Eosinophilic enteropathy is a condition that causes a type of white blood cell called an eosinophil to build up in the gastrointestinal system and in the blood. Eosinophils play a role in the body’s immune response by releasing toxins. Eosinophils are associated with allergic-type reactions, but their specific function is largely unknown.When eosinophils build up in the gastrointestinal tract, this begins to affect the body by causing polyps, tissue break down, inflammation, and ulcers. Eosinophilic enteropathy can occur in children or adults and is characterized by intolerance to some foods. Eosinophilic enteropathy can affect any part of the gastrointestinal tract, and is often named by the part affected: colon (colitis), esophagus (esophagitis), stomach (gastritis), or both the stomach and small intestine (gastroenteritis).[1][2]
Last updated: 12/25/2015

References

  1. Fleischer D & Atkins D. Evaluation of the patient with suspected eosinophilic gastrointestinal disease. Immunology and Allergy Clinics of North America. 2009; 29(1):53-63, ix. http://www.ncbi.nlm.nih.gov/pubmed/19141341. Accessed 12/25/2015.
  2. Eosinophilic Esophagitis (EoE). American Partnership for Eosinophilic Disorders. 2015; http://apfed.org/about-ead/egids/eoe/. Accessed 12/25/2015.
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Basic Information

  • The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Eosinophilic enteropathy. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Eosinophilic gastroenteritis
  • Eosinophilic gastritis
  • Eosinophilic enteritis
  • Eosinophilic gastroenteropathy
  • Eosinophilic esophagitis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.