Other Names for this Disease
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the scalp-limited form and the generalized form, in which all body hair is affected. The progressive thinning of the hair shaft is a typical feature of androgenetic alopecia. Hypotrichosis simplex can be inherited either as an autosomal dominant or autosomal recessive trait. Some cases are caused by mutations in the APCDD1 gene on chromosome 18p11. To date, there is no treatment for this condition.Hypotrichosis simplex is a rare form of hereditary hair loss without other abnormalities. Affected individuals typically show normal hair at birth, but experience hair loss and thinning of the hair shaft that starts during early childhood and progresses with age. Hypotrichosis simplex can be divided into 2 forms:
Last updated: 7/12/2011
- Hypotrichosis simplex, Generalized, Heriditary. Online Mendelian Inheritance in Man (OMIM). 2011; http://omim.org/entry/605389. Accessed 7/12/2011.
- Betz RC. Hypotrichosis simplex. Orphanet. 2010; http://www.orpha.net/consor/cgi-bin/Disease_Search.php?lng=EN&data_id=10760&Disease_Disease_Search_diseaseGroup=Hypotrichosis-simplex&Disease_Disease_Search_diseaseType=Pat&Disease(s)/group of diseases=Hypotrichosis-simplex&title=Hypotrichosis-simplex&search=Disease_Search_Simple. Accessed 7/12/2011.
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- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
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