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Diseases

Genetic and Rare Diseases Information Center (GARD)

Sinonasal undifferentiated carcinoma


Other Names for this Disease
  • SNUC
  • Highly aggressive undifferentiated carcinoma of the nasal cavity and paranasal sinuses
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Overview

Sinonasal undifferentiated carcinoma (SNUC) is a type of cancer that develops in the sinuses of the head.  SNUC occurs when cells from the layer of tissue that lines the sinuses (called the epithelium) rapidly increase in number, forming a mass.  The first symptoms of SNUC may include difficulty breathing though the nose or mild facial pain.  As SNUC progresses, other symptoms may include nosebleeds, facial numbness, or tingling in the face.  SNUC is an aggressive cancer, meaning it grows rapidly and has a tendency to spread into healthy tissues nearby and to more distant parts of the body (metastasis).  Treatment may include surgery, chemotherapy, and radiation therapy.[1]
Last updated: 1/22/2013

References

  1. Schmidt ER, Berry RL. Diagnosis and treatment of sinonasal undifferentiated carcinoma: report of a case and review of the literature. Journal of oral and maxillofacial surgery. 2008; 66:1505-1510. http://www.ncbi.nlm.nih.gov/pubmed/18571040. Accessed 1/15/2013.
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Basic Information

  • The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.

In Depth Information

  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Sinonasal undifferentiated carcinoma. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • SNUC
  • Highly aggressive undifferentiated carcinoma of the nasal cavity and paranasal sinuses
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.