Merkel cell carcinoma
Other Names for this Disease
- Merkel cell cancer
- Merkle tumors
- Carcinoma, merkel cell
- Cutaneous neuroendocrine carcinoma
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lymph nodes, or more distant parts of the body. Merkel cell polyomavirus has been detected in about 80% of the tumors tested. It is thought that this virus can cause somatic mutations leading to MCC when the immune system is weakened. Other risk factors for developing MCC include ultraviolet radiation and being over 50 years of age. Treatment should begin early and depends on the location and size of the cancer, and the extent to which it has spread.Merkel cell carcinoma (MCC) is a rare type of skin cancer that usually appears as a single, painless, lump on sun-exposed skin. It is typically red or violet in color. It is considered fast-growing and can spread quickly to surrounding tissues, nearby
Last updated: 10/6/2014
- National Cancer Institute. General Information about Merkel Cell Carcinoma. Merkel Cell Carcinoma Treatment. 2011; http://www.cancer.gov/cancertopics/pdq/treatment/merkelcell/healthprofessional. Accessed 5/22/2011.
- The American Cancer Society provides detailed information about Merkel cell carcinoma. Click on the link to access this information.
- DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
- The Merck Manual provides information on this condition for patients and caregivers.
- The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.
- SkinCancerNet is a comprehensive online skin cancer information resource developed by the American Academy of Dermatology. Click on the link to view information on Merkel cell carcinoma.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Merkel cell carcinoma. Click on the link to view a sample search on this topic.