- Nodose hair
Your QuestionMy daughter has monilethrix. Are there any clinical trials underway for this disorder? Any stem cell research? Is there is anything out there that might help, now or in the future?
We have identified the following information that we hope you find helpful. If you still have questions, please contact us.
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The National Institutes of Health, through the National Library of Medicine, developed ClinicalTrials.gov to provide patients, family members, and members of the public with current information on clinical research studies. No studies involving monilethrix are listed at this time, but check this site often for updates. To search for a study, use "monilethrix" as your search term.
You can also contact the Patient Recruitment and Public Liaison (PRPL) Office at the National Institutes of Health (NIH). We recommend calling the toll-free number listed below to speak with a specialist, who can help you locate relevant clinical trials.
Patient Recruitment and Public Liaison Office (PRPL)
NIH Clinical Center
Bethesda, Maryland 20892-2655
Web site: http://clinicalcenter.nih.gov/
While there is no recognized definitive treatment for monilethrix, oral acitretin and topical 2% minoxidil have shown good clinical and cosmetic results with continued use. The systemic administration of vitamins, retinoids, griseofulvin, oral contraceptives, steroids, radiation therapy, external desquamative ointments, and steroid preparations have not show impressive results.
Avoiding trauma is perhaps the most effective method of managing monilethrix. This is because from birth, the hair of individuals with monilethrix tends to have an increased susceptibility to weathering and cosmetic damage (e.g., sunlight exposure, dyeing, bleaching, perming, curling). This susceptibility to damage can prevent hair from growing to its maximum length.
- Kliegman RM, Behrman RE, Jenson HB, Stanton BF. Chapter 661 - Disorders of Hair. Kliegman: Nelson Textbook of Pediatrics, 18th ed. Philadelphia, PA: Saunders, An Imprint of Elsevier; 2007;
- Schwartz RA, Alexiewicx-Slowinska M. Monilethrix. Medscape Reference. September 8, 2015; http://emedicine.medscape.com/article/1118500-overview#. Accessed 10/5/2015.
- Karincaoglu Y, Coskun BK, Seyhan ME, Bayram N. Monilethrix: improvement with acitretin. Am J Clin Dermatol. 2005; http://www.ncbi.nlm.nih.gov/pubmed?term=16343029. Accessed 1/31/2012.
- Rossi A, Iorio A, Scali E, Fortuna MC, Mari E, Palese E, Greco P, Carlesimo M. Monilethrix treated with minoxidil. Int J Immunopathol Pharmacol. 2011; http://www.ncbi.nlm.nih.gov/pubmed?term=21496408. Accessed 1/31/2012.