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Diseases

Genetic and Rare Diseases Information Center (GARD)

Anal cancer


Other Names for this Disease
  • Cancer of the anus
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Anal cancer is a rare form of cancer that occurs due to abnormal and uncontrolled cell growth in the anus. Signs and symptoms of the condition include rectal bleeding; a lump in or near the anus; anal pain; itching; changes in bowel habits; and/or swollen lymph nodes. In most cases, the underlying cause of anal cancer is unknown. There appears to be a link between anal cancer and the human papillomavirus (HPV) infection. Other risk factors for anal cancer include HIV infection, sexual activity, smoking, and a weakened immune system. The best treatment options for anal cancer depend on many factors including the stage of the condition, the location of the tumor and if there are associated conditions (i.e. HIV) but may include surgery, chemotherapy, and radiation therapy.[1][2][3]
Last updated: 6/3/2016

References

  1. Anal Cancer. MedlinePlus. October 2014; https://www.nlm.nih.gov/medlineplus/ency/article/007652.htm.
  2. Anal Cancer Treatment (PDQ®)–Patient Version. National Cancer Institute. May 2015; http://www.cancer.gov/types/anal/patient/anal-treatment-pdq#section/_1.
  3. Anal Cancer. American Cancer Society. January 2016; http://www.cancer.org/acs/groups/cid/documents/webcontent/003083-pdf.pdf.
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Basic Information

  • The American Cancer Society provides information on Anal cancer. Please click on the link to access this resource.
  • The Mayo Clinic Web site provides further information on Anal cancer.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.

In Depth Information

  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Anal cancer. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Cancer of the anus
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.