Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Childhood hepatocellular carcinoma


Other Names for this Disease
  • Childhood Carcinoma of Liver Cell
  • Childhood Hepatoma
  • Childhood Liver Cell Carcinoma
  • Pediatric Carcinoma of Liver Cell
  • Pediatric Hepatocellular Carcinoma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

Newline Maker

How might childhood hepatocellular carcinoma be treated?

The treatment for childhood hepatocellular carcinoma (childhood HCC) is dependent on a number of factors including the PRETEXT and POSTTEXT group. This is a way of describing the tumor before treatment (PRETEXT) and after treatment (POSTTEXT). The course of treatment is additionally dependent on whether or not a tumor can be initially removed with surgery and whether the cancer has spread (metastasized) to other parts of the body.[1][2] 

Treatment options for a tumor that can be removed by surgery at the time of diagnosis may include:[1][2]
Treatment options for a tumor that cannot be removed by surgery at the time of diagnosis may include:[1][2][3]
Treatment for a childhood HCC that has spread to other parts of the body may include a combination of chemotherapy and surgery to remove as much of the tumor from the liver as possible as well as other places where the cancer has spread. If the childhood HCC is related to a hepatitis B viral infection, treatment may additionally include antiviral medications.[2]
Last updated: 7/14/2016

References
  1. Deirdre Kelly, Khalid Sharif, Rachel M. Brown, Bruce Morland. Hepatocellular Carcinoma in Children. Clin Liver Dis. May 2015; 19(2):433-447. http://www.ncbi.nlm.nih.gov/pubmed/25921672.
  2. Childhood Liver Cancer Treatment (PDQ®)–Patient Version. National Cancer Institute. June 20, 2016; http://www.cancer.gov/types/liver/patient/child-liver-treatment-pdq#link/_247_toc.
  3. Pr Piotr CZAUDERNA. Pediatric hepatocellular carcinoma. Orphanet. November 2014; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=33402.


Management Guidelines

  • The National Cancer Institute offers information for health professionals on the treatment of childhood liver cancer including Childhood hepatocellular carcinoma

Clinical Trials & Research for this Disease

  • Orphanet lists European clinical trials, research studies, and patient registries enrolling people with this condition. 
  • The Research Portfolio Online Reporting Tool (RePORT) provides access to reports, data, and analyses of research activities at the National Institutes of Health (NIH), including information on NIH expenditures and the results of NIH-supported research. Although these projects may not conduct studies on humans, you may want to contact the investigators to learn more. To search for studies, enter the disease name in the "Text Search" box. Then click "Submit Query".
Other Names for this Disease
  • Childhood Carcinoma of Liver Cell
  • Childhood Hepatoma
  • Childhood Liver Cell Carcinoma
  • Pediatric Carcinoma of Liver Cell
  • Pediatric Hepatocellular Carcinoma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.