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Diseases

Genetic and Rare Diseases Information Center (GARD)

Childhood ovarian cancer


Other Names for this Disease
  • Ovarian carcinoma, childhood
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Overview

Childhood ovarian cancer is a rare type of cancer that occurs due to abnormal and uncontrolled cell growth in the ovaries. The childhood form, specifically, is extremely rare and accounts for less than 5% of all ovarian cancer cases. The most common types of ovarian cancers diagnosed in children and adolescents include germ cell tumors, followed by epithelial tumors, stromal tumors, and then other tumors (such as Burkitt lymphoma and small cell carcinoma of the ovary).[1][2][3] Many people with early ovarian cancer have no signs or symptoms of the condition. When present, symptoms may include painful menstrual periods; an abdominal lump; pain or swelling in the abdomen; having male sex traits (i.e. body hair or a deep voice); and/or early signs of puberty. The underlying cause of childhood ovarian cancer is often unknown. Certain inherited conditions, such as Ollier disease, Maffucci syndrome and Peutz-Jeghers syndrome are associated with an increased risk of developing childhood ovarian cancer.[1] Treatment varies based on many factors including the type of ovarian tumor and the severity of the condition. It may include surgery, radiation therapy, and/or chemotherapy.[1][3]
Last updated: 4/6/2016

References

  1. Unusual Cancers of Childhood Treatment–Patient Version (PDQ®). National Cancer Institute. October 2015; http://www.cancer.gov/types/childhood-cancers/patient/unusual-cancers-childhood-pdq#link/_128_toc.
  2. Marc R Laufer, MD. Ovarian cysts and neoplasms in infants, children, and adolescents. UpToDate. October 2015;
  3. Ruttenstock EM, Saxena AK, Schwinger W, Sorantin E, Hoellwarth ME. Pediatric ovarian tumors--dilemmas in diagnosis and management. Eur J Pediatr Surg. 2010 Mar;20(2):116-20. March 2010; 20(2):116-120.
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Basic Information

  • Mayo Clinic has an information page on Childhood ovarian cancer.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Childhood ovarian cancer. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Ovarian carcinoma, childhood
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.