Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Waterhouse–Friderichsen syndrome


Other Names for this Disease
  • Fatal pneumococcal Waterhouse-Friderichsen syndrome
  • Waterhouse-Friderichsen syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Waterhouse–Friderichsen syndrome is adrenal gland failure due to bleeding into the adrenal gland. It is usually caused by severe meningococcal infection or other severe, bacterial infection. Symptoms include acute adrenal gland insufficiency, and profound shock.[1] Most patients with this condition are children, although adults may rarely be affected.[2] It is deadly if not treated immediately.[1][2]

Last updated: 2/4/2016

References

  1. Vyas JM, Zieve D, Black B. Waterhouse-Friderichsen syndrome. MedlinePlus. September 1, 2013; http://www.nlm.nih.gov/medlineplus/ency/article/000609.htm.
  2. Tritos NA. Adrenal Hemorrhage. Medscape Reference. August 27, 2014; http://emedicine.medscape.com/article/126806-overview.
GARD Video Tutorials
GARD Video Tutorials
Learn how to find information on treatment, research, specialists, and more.
Your Questions Answered
Your Questions Answered
View questions about this condition answered by GARD Information Specialists. You can also submit a new question.

Basic Information

  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.

In Depth Information

  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Waterhouse–Friderichsen syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Fatal pneumococcal Waterhouse-Friderichsen syndrome
  • Waterhouse-Friderichsen syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.