- Idiopathic retroperitoneal fibrosis
- Ormond's disease
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Corticosteroids are tried first. Dosing will be prescribed on a case by case basis, but doses often vary between 30 and 60 mg per day. Corticosteroids are then tapered slowly. Some people with retroperitoneal fibrosis may continue on low dose maintenance therapy for up to 2 years. If corticosteroid treatment doesn't work, a biopsy should be done to confirm the diagnosis. Other medicines to suppress the immune system, such as mycophenolate mofetil, methotrexate, azathioprine, cyclophosphamide or tamoxifen can be prescribed alone or in combination with corticosteroids. When medicine does not work, surgery and stents (draining tubes) are considered. Stents (drainage tubes) placed in the ureter or in the renal pelvis may provide short-term relief of the symptoms until the condition is surgically treated. Surgery aims to remove the mass and/or free the ureters.
- Vorvick LJ. Retroperitoneal fibrosis. MedlinePlus. March 17, 2011; http://www.nlm.nih.gov/medlineplus/ency/article/000463.htm. Accessed 10/15/2013.
- Vaglio A, Salvarani C, Buzio C. Retroperitoneal fibrosis. Lancet. 2006; http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=DetailsSearch&Term=16427494%5Buid%5D. Accessed 10/15/2013.
- Tzou M, Gazeley DJ, Mason PJ. Retroperitoneal fibrosis. Vasc Med. 2014 Oct; 19(5):407-14. Accessed 4/22/2015.
- ClinicalTrials.gov lists trials that are studying or have studied Retroperitoneal fibrosis. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.