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Diseases

Genetic and Rare Diseases Information Center (GARD)

Papillary renal cell carcinoma


Other Names for this Disease
  • RCCP
  • Renal adenocarcinoma
  • Papillary renal cell carcinoma, sporadic - (subtype)
  • Papillary renal cell carcinoma, bilateral - (subtype)
  • Papillary renal cell carcinoma, multiple - (subtype)
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Papillary renal cell carcinoma (PRCC) is a type of cancer that occurs in the kidneys. It accounts for about 10-15% of all renal cell carcinomas.[1]Renal cell carcinomas are a type of kidney cancer that develop in the lining of very small tubes (tubules) in the kidney.[2]The term "papillary" describes the finger-like projections that can be found in most of the tumors.[3] PRCC can be divided into two types: type 1, which is more common and usually grows more slowly and type 2, which are usually more aggressive .[1]Though the exact cause of papillary renal cell carcinoma is unknown, smoking, obesity, and genetic predisposition conditions (such as hereditary leiomyomatosis and renal cell cancer) may contribute to the development of this type of cancer. Treatment often begins with surgery to remove as much of the cancer as possible, and may be followed by radiation therapy, chemotherapy, biological therapy, or targeted therapy.[3]
Last updated: 2/11/2016

References

  1. Michael B Atkins, Toni K Choueiri. Epidemiology, pathology, and pathogenesis of renal cell carcinoma. UpToDate. November 24, 2015;
  2. Renal cell carcinoma. MedlinePlus. 3/23/2014; https://www.nlm.nih.gov/medlineplus/ency/article/000516.htm.
  3. Kidney Cancer (Adult)-Renal Cell Carcinoma. American Cancer Society. 2/24/2014; http://www.cancer.org/acs/groups/cid/documents/webcontent/003107-pdf.pdf.
  4. National Cancer Institute. General Information about Renal Cell Carcinoma. Renal Cell Cancer Treatment. July 7, 2015; http://www.cancer.gov/cancertopics/pdq/treatment/renalcell/Patient/page1.
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Basic Information

  • Cancer.Net provides oncologist-approved cancer information from the American Society of Clinical Oncology and has information about Papillary renal cell carcinoma.
  • The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.

In Depth Information

  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Papillary renal cell carcinoma. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • RCCP
  • Renal adenocarcinoma
  • Papillary renal cell carcinoma, sporadic - (subtype)
  • Papillary renal cell carcinoma, bilateral - (subtype)
  • Papillary renal cell carcinoma, multiple - (subtype)
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.