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Diseases

Genetic and Rare Diseases Information Center (GARD)

Clear cell renal cell carcinoma


Other Names for this Disease
  • Clear cell RCC
  • Cystic-multilocular variant
  • Clear-cell metastatic renal cell carcinoma (subtype)
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Overview

Clear cell renal cell carcinoma is a cancer of the kidney.  The name "clear cell" refers to the appearance of the cancer cells when viewed with a microscope.[5258]  Clear cell renal cell carcinoma occurs when cells in the kidney quickly increase in number, creating a lump (mass).  Though the exact cause of clear cell renal cell carcinoma is unknown, smoking, the excessive use of certain medications, and several genetic predisposition conditions (such as von Hippel Lindau syndrome) may contribute to the development of this type of cancer.  Treatment often begins with surgery to remove as much of the cancer as possible, and may be followed by radiation therapy, chemotherapy, biological therapy, or targeted therapy.[1]
Last updated: 6/1/2012

References

  1. National Cancer Institute. General Information about Renal Cell Carcinoma. Renal Cell Cancer Treatment. July 7, 2015; http://www.cancer.gov/cancertopics/pdq/treatment/renalcell/Patient/page1.
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In Depth Information

  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Clear cell renal cell carcinoma. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Clear cell RCC
  • Cystic-multilocular variant
  • Clear-cell metastatic renal cell carcinoma (subtype)
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.