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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Multicentric Castleman Disease


Other Names for this Disease
  • Idiopathic multicentric Castleman's disease
  • MCD
  • Multicentric angiofollicular ganglionic hyperplasia
  • Multicentric angiofollicular lymph hyperplasia
  • Multicentric Castleman's disease
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Your Question

How might multicentric Castleman's disease be treated?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

How might multicentric Castleman disease be treated?

The treatment of multicentric Castleman disease (MCD) varies based on the severity of the condition and whether or not the patient has an HIV and/or human herpes virus type 8 (HHV-8) infection. Possible treatment options include:[1][2][3]
  • Immunotherapy can be used to block the action of the interleukin-6 (IL-6), a protein that is produced in excess by the immune system of people with MCD
  • Chemotherapy may be recommended to slow the growth of lymphatic cells
  • Corticosteroid medications can reduce inflammation
  • Anti-viral drugs can block the activity of HHV-8 or HIV (in people who are infected by these viruses)
Last updated: 6/25/2015

References
Other Names for this Disease
  • Idiopathic multicentric Castleman's disease
  • MCD
  • Multicentric angiofollicular ganglionic hyperplasia
  • Multicentric angiofollicular lymph hyperplasia
  • Multicentric Castleman's disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.