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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Multicentric Castleman Disease


Other Names for this Disease
  • Idiopathic multicentric Castleman's disease
  • MCD
  • Multicentric angiofollicular ganglionic hyperplasia
  • Multicentric angiofollicular lymph hyperplasia
  • Multicentric Castleman's disease
Related Diseases
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Your Question

Does the multicentric form of Castleman's disease always cause symptoms?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

What are the signs and symptoms of multicentric Castleman disease?

The signs and symptoms of multicentric Castleman disease (MCD) are often nonspecific and blamed on other, more common conditions. They can vary but may include:[1][2][3]
Less commonly (<10% of cases), people affected by MCD will have no signs or symptoms of the condition.[2]

Other conditions associated with MCD include amyloidosis, POEMS syndrome, autoimmune disease, hemolytic anemia, and immune thrombocytopenic purpura (ITP).[2]
Last updated: 6/25/2015

References
Other Names for this Disease
  • Idiopathic multicentric Castleman's disease
  • MCD
  • Multicentric angiofollicular ganglionic hyperplasia
  • Multicentric angiofollicular lymph hyperplasia
  • Multicentric Castleman's disease
Related Diseases
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.