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Diseases

Genetic and Rare Diseases Information Center (GARD)

Human T-cell leukemia virus type 1


Other Names for this Disease
  • HTLV-1
  • Human T lymphotropic virus type 1
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Human T-cell leukemia virus, type 1 (HTLV-1) is a retroviral infection that affect the T cells (a type of white blood cell). Although this virus generally causes no signs or symptoms, some affected people may later develop adult T-cell leukemia (ATL), HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) or other medical conditions.[1] HTLV-1 is spread by blood transfusions, sexual contact and sharing needles. It can also be spread from mother to child during birth or breast-feeding. There is no cure or treatment for HTLV-1 and it is considered a lifelong condition; however, most (95%) infected people remain asymptomatic (show no symptoms) throughout life.[2][3]
Last updated: 12/10/2014

References

  1. David T Scadden, MD; Andrew R Freedman, FRCP; Paul Robertson, MRCP. Human T-lymphotropic virus type I: Virology, pathogenesis, and epidemiology. UpToDate. June 2014;
  2. HTLV Type I and Type II. NORD. May 2012; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/1203/viewAbstract.
  3. Ewa Maria Szczypinska, MD. Human T-Cell Lymphotropic Viruses. Medscape. August 2014; http://emedicine.medscape.com/article/219285-overview.
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Basic Information

  • The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Human T-cell leukemia virus type 1. Click on the link to view a sample search on this topic.

Selected Full-Text Journal Articles

Other Names for this Disease
  • HTLV-1
  • Human T lymphotropic virus type 1
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.