Lattice corneal dystrophy type 1
Other Names for this Disease
- Corneal dystrophy, lattice type 1
cornea, the clear outer covering of the eye. In order to see properly, the cornea must remain clear. In LCD1, a protein, known as amyloid, builds up in a layer of the cornea called the stroma. Symptoms usually become apparent in childhood or adolescence and may include separation of layers of the cornea (corneal erosions), decreased vision, photosensitivity, and eye pain. LCD1 is caused by mutations in the TGFBI gene and is inherited in an autosomal dominant manner. Treatment focuses on relieving erosions with antibiotics and bandage contact lenses. If treatment is not successful and erosions become recurrent, phototherapeutic keratectomy to smooth the corneal surface and corneal transplant may be considered.Lattice corneal dystrophy type 1 (LCD1) is an eye disorder that affects the
Last updated: 5/13/2016
- Natalie A Afshari, Stuart I Brown. Lattice Corneal Dystrophy. Medscape. Sep 22, 2014; http://emedicine.medscape.com/article/1193793-overview.
- lattice corneal dystrophy type I. Genetics Home Reference. April 2012; https://ghr.nlm.nih.gov/condition/lattice-corneal-dystrophy-type-i.
- Genetics Home Reference (GHR) contains information on Lattice corneal dystrophy type 1. This website is maintained by the National Library of Medicine.
- The National Eye Institute (NEI) was established by Congress in 1968 to protect and prolong the vision of the American people. Click on the link to view information on this topic.
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- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
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